Journal of Pure and Applied MicrobiologyVol. 7 No. 1

Determining Total Phenolic Content of Paeonia sinjiangensis K.Y. Pan and its Antimicrobial Activity Grown in Xinjiang, China

Haiyan Gong1, Lanying Hu1, Chen Zhang1, Ming Zhu2, Bin He1, Qingling Geng1, Bo Zhang3 and Xuehan Wang1*

1The Fifth Affiliated Hospital of Xinjiang Medical University, Urumqi - 830 000, Xinjiang, China. 2Xinjiang Medical University, Urumqi - 830 000, Xinjiang, China. 3The First People?s Hospital of Wenling City, Wenling - 317 500, Zhejiang, China.

Received on 08 January 2013 and accepted on 04 March 2013

 

ABSTRACT

Paeonia sinjiangensis K. Y. Pan is a perennial herb belonging to the family Ranunculaceae which is one of the most important crude drugs in traditional Chinese medicine, used as an anti-inflammatory, analgesic and sedative agent. This paper deals with the detailed total phenolic content of the crude drug Paeonia sinjiangensis K.Y. Pan, from Xinjiang, China. Meanwhile, it tested for antimicrobial activity in this study. The total phenolic content of Paeonia sinjiangensis K.Y. Pan was 9.58 ? 1.03 mg QE/g dry wt. The microscopic characteristics were investigated, which offer data to differentiate the drug from its other species. It showed strong inhibition against Blastomyces albicans and possessed considerable activity against Staphylococcus aureus and Escherichia coli.

Keywords : Antimicrobial activity, Paeonia sinjiangensis K.Y. Pan, phenolics.