S. Mailafia1, W. Nafarnda2 and M.Y. Sugun3
1Faculty of Veterinary Medicine, Department of Veterinary Microbiology, University of Abuja, Nigeria.
2Department of Veterinary Public Health and Preventive Medicine, University of Abuja, Nigeria.
3Department of Veterinary Microbiology and Parasitology, University of Maiduguri, Nigeria.
The present studyis the first to be conducted in order to determine the occurrence and antimicrobial susceptibility pattern of Aeromonashydrophilastrains from diarrheic patientsattending University of Abuja Teaching Hospital in Nigeria.A total of 153 stool samples were collected from out patients attending University of Abuja Teaching Hospital (UATH). The diarrhoeic patients were screened for the presence of Aeromonashydrophila using routine cultural methods and biochemical characterization. Our results did show that the overall isolation rate is (3. 92%). The prevalence per age group is presented showed that age group 26-30 years having the highest rate of (1.31%) of the total sample analysed. Age groups 11-15 and 16-20 years having the same prevalence rate of (0.65%) each, while the age groups ≤5, 6-10 and >30 had no prevalence for Aeromonashydrophila. The distribution of A. hydrophilainfection among different sexes has shown that(2.22%) out of the sixA.hydrophila were isolated from diarrheic stools collected from males, while (6.35%) were isolated from females.Statistical analysis showed that X2yates corrected)= 0.05 P= 0.596, OR=1.10 (0.50<OR<2.80).This indicated the level of association between age and rate of Aeromonas infection.Antimicrobial susceptibility patterns of A.hydrophila showed that the isolates were extremely (100%) resistant to Ampicillin, Cephalothin, Gentamicin, Streptomycin, Sulphatriazone, Tetracyclin and Cotrimoxazole. All the isolates are highly susceptible to Colistin and Ceftazidime (100%) followed by Augmentin (83%). They are moderately susceptible to Cefutoxime 50%). Earlier studies revealed resistance to Tetracycline and Cotrimoxazole.Our study confirmed that Aeromonashydrophila as an importantenteropathogenresponsiblefordiarrhoea in humans in Gwagwalada. Diagnostic regime should involve screening of this organism alongside other microorganisms responsible for diarrhoeic symptoms in man and animals.This is the first report to involve Aeromonashydrophila in human diarrhoea and sought regime for choice of antibiotics for the management of the infection.
Keywords: Aeromonas, diarrhoea, antibiotic, susceptibility testing, Occurrence.